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FTS Systems
SMART Freeze Drying
SMART Freeze-Dryer Technology is a patented system that puts the experience of the world’s top lyophilization scientists into an easy-to-use cycle development tool. Developed exclusively with leading academics at The University of Connecticut and Purdue University, this technology is available on the LyoStar II freeze-dryer (including a retrofit option for existing LyoStar II systems).
SMART Freeze-Dryer technology eliminates the trial-and-error approach normally involved in developing new lyophilization cycles. It enables experts and novices alike to develop new cycles quickly, while also ensuring that those cycles are elegant and efficient.
The SMART tools provide instant feedback on important product data — such as product resistance, heat flow, and product thickness — that was previously unavailable.
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KEY FEATURES
- SMART Freeze Dryer Technology (PLC) helps automate and shorten the development of the freeze drying cycle
- Get product information that has previously been unavailable – such as product resistance, heat flow and product thickness
- Designed to minimize issues with transfer of freeze drying cycles to your production freeze dryer
- Easy to use operator interface
- Clean room configurations available
- Condenser coil type configuration to maximize condenser efficiency
- 316 SS shelf design with 316SS stoppering ram (optional) and condenser
- Selection of pressure and temperature sensors to meet any requirement.
- Available with optional 21 CFR Part 11
KEY BENEFITS
- Substantially decrease cycle development time with SMART
- Understand more about your product and its obstacles and opportunities in lyophilization cycle development
- Easily transfer cycles to larger systems
- Increase ROI with greater throughput and optimized cycles
- Spend more time looking at formulation strategies to maximize product effectiveness
- Developed by lyophilization scientists for lyophilization scientists
HOW TO SELECT
To configure a LyoStar II with SMART Freeze Dryer Technology to fit your requirements, select options from each of the groups below. For assistance in determining which option is right for you or to receive a quote, please contact a product specialist. We will be glad to discuss with you the options and their importance and use.
SPECIFICATIONS
| Specification |
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| Shelf Temperature Control Range (°C) |
-70 to +60C
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| Lowest Condenser Temperature |
-85C
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| Maximum Condenser Capacity (L) |
30 L
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| Condenser Surface Area (in2 / cm2) |
828 / 5481
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Maximum Ice Condensing Capacity in 24 hours (L)
This specification is based on freeze drying water as aggessively as possible.
The ability to collect ice is application dependent and your actual rate will most likely be lower |
20
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| Condenser Pull-Down from 20 °C to -75 °C (minutes) |
< 10
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Shelf Pull-Down from 20 °C to -40 °C
(minutes) |
< 25
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| Vacuum Time to 100 Millitorr (minutes) |
< 20
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| Lowest System Vacuum (mT) |
< 10
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| Temperature Uniformity (°C)\\ |
+/- 1.0C
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| Shelf Configuration |
| Number of Shelves |
Shelf Area
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Shelf Clearance
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Shelf Clearance with Optional Shelf Latching
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Bulk and Stoppering** (ft2 / cm2)
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Bulk and Stoppering** (in / mm)
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1 Shelf Latched (in / mm)
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2 Shelves Latched (in / mm)
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| 1 Shelf |
1.5 / 1394
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9.5 / 241
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| 2 Shelves |
3.1 / 2880
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4.5 / 114
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9.25 / 235
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| 3 Shelves |
4.6 / 4274
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2.8 / 71
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4.25 / 108
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8.5 / 216
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| 4 Shelves |
6.1 / 5667
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2.0 / 51
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2.6 / 66
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4.0 / 102
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| 5 Shelves |
7.6 / 7061
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1.5 / 38
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| Dimensional Data |
| Width (in / cm) |
33 / 84
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| Depth (in / cm) |
43 / 109
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| Height (in / cm) |
75 / 190
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| Approximate Weight (lb / kg) |
1300 / 590
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| Minimum Clearance on All Sides (ft / cm) |
2 / 61
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APPLICATION EXAMPLES
- Laboratory research and development and/or small production freeze drying
- Process development with intent to move process to clinical size freeze dryer
- Serum bottles and vials
OPTIONAL COMPONENTS
ACCESSORIES
VirTis 96 Well Freeze Drying Systems (pdf)
Freeze-Drying Product Sensors (pdf)
| yoStar II Accessories |
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| Model Number |
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Description |
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| VP200 |
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200 liters per minute vacuum pump |
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| Options |
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| Voltage |
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C |
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208V/60Hz |
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D |
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220V/50Hz |
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| OME-06 |
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Oil mist eliminator for VP100 |
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| FDPS13 |
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Special product sensor, 13mm |
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| FDPS20 |
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Special SS encased product sensor, 20mm |
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| TS-1120 |
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Bulk tray 11" x 20" |
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| TRB-1120 |
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Removable bottom tray 11" x 20" |
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| LYO-LGT |
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WL Gore LyoGuard Trays |
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| LYO-RDT |
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WL Gore LyoGuard R&D Trays |
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| LYO-SE |
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Sample extractor |
| Options |
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A |
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120V/60Hz |
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Q |
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195-230V/ 50 or 60Hz |
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