Dr. Tom Anchordoquy, Associate Professor
University of Colorado
Email: Tom.Anchordoquy@ucdenver.edu
Dr. Anchodoquy is a Member, Center for Pharmaceutical Biotechnology and University of Colorado Cancer Center. His educational background includes his receipt of a BS from Oregon State University in Biology, his MA, PhD, University of California at Davis (Zoology), and Postdoctoral Fellow, University of Colorado at Boulder and University of Colorado Denver.
His laboratory focuses on the development of synthetic delivery systems for use in nucleic acids-based therapies (e.g., gene, siRNA, antisense, aptamers). Their most recent work utilizes an unconventional approach toward developing lipid-based delivery systems that possess prolonged circulation lifetimes and target tumors. Studies on the delivery systems include biophysical characterization, pharmaceutical optimization, cell culture assessment, and ultimately testing in animal models.
Dr. Anchordoquy has co-authored numerous including titles such as In vivo comparative study of Lipid/DNA complexes with different in vitro serum stability: effects on biodistribution and tumor accumulation. J. Pharm. Sci., 97: 237-50 (2008). Metal Contaminants Promote Degradation of Lipid/DNA Complexes during Lyophilization. Biochimica et Biophysica Acta Biomembranes 1768(3): 669-77 (2007) and Rationale for the Selection of an Aerosol Delivery System for Gene Delivery. Journal of Aerosol Medicine 19 (3): 372-384 (2006).
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