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Freeze Dryers / Lyophilizers / BenchTop Tray Lyophilizers / AdVantage Plus BenchTop Freeze Dryer
 
AdVantage Plus BenchTop Freeze Dryer

VirTis
AdVantage Plus BenchTop Freeze Dryer

The AdVantage Plus freeze dryer provides a product environment similar to pilot models, in a small bench-top configuration. Shelf temperatures as low as -55C and condenser temperatures to -85C supports a wide range of applications. Available in bulk or stoppering configurations and with up to 3 shelves and an internal condenser. The AdVantage Plus allows you to configure a bench-top freeze dryer with pilot scale freeze dryer capabilities.


KEY FEATURES

  • Compact, bench-top design
  • Easy scale up from the AdVantage Plus to larger pilot scale freeze dryers
  • 316 SS shelf design within a 304 SS chamber
  • Clear acrylic door for easy product viewing during processing
  • Stoppering or bulk configurations
  • On-board Wizard controller.

KEY BENEFITS

  • Choice of refrigeration package allows you to configure a system to meet your own needs
  • Ease of scale up
  • Pilot scale capabilities in a bench-top size freeze dryer
  • Manifold or tray type drying
  • Easy install, requires standard laboratory utilities
  • Accommodate a wide array of products with shelf temperatures to -65C and condensers to -85C

HOW TO SELECT

Advantage-Plus-(1).JPG

SPECIFICATIONS

Specification
 ES
XL
EL
Shelf Temperature Control Range (°C)
-40 to 60C
-40 to 60C
-55 to 60C
Lowest Shelf
Temperature
(50 Hz / 60 Hz, °C)
-42C / -45C
-57C / -60C
-62C / -65C
Lowest Condenser Temperature
(50 Hz / 60 Hz, °C)
-50C /-53C
-67C / -70C
-82C / -85C
Maximum Condenser Capacity (L)
6L
Maximum Ice Condensing Capacity in 24 hours (L)
This specification is based on freeze drying water as aggessively as possible. 
The ability to collect ice is application dependent and your actual rate will most likely be lower
4 L
Shelf  Pull-Down from 20 °C to -45 °C (minutes)
≤ 25 minutes
Shelf Pull-Down from
20 °C to -40 °C
(minutes) ¶
≤ 45
≤ 40
≤ 30
Temperature
Uniformity (°C)\\
± 1.0
Note: Performance specifications are based on SP Industries test data from units operating at an ambient room temperature of approximately 20 °C. SP Industries recommends an operating range of 15-25 °C (59-77 °F).


Dimensional Data
Width (in. / mm)
25.75 / 654
Depth (in. / mm)
28 / 711
Height (in. / mm)
28.75 / 730
Approximate
Weight (lb / kg)\\
320 / 145


Shelf Configuration
Number of Shelves
Shelf Clearance
(in. / mm)
Shelf Area
(in.2 / cm2)
1 Shelf
6.25 / 158
150 / 970
2 Shelves
2.87 / 73
300 / 1,940
3 Shelves
1.75 / 44.5
450 / 2,910


Additional Information
Shelf Construction
316L Stainless Steel
Chamber Construction
304 Stainless Steel
Chamber Door
Full-View Acrylic
Nominal Shelf Size
(W x D x TH)
10.75 in. X 14 in. X 0.75 in.
(273 mm X 355 mm X 19 mm)
Vacuum Pump
(Required, not included)
Two-Stage Rotary Vane
or Suitable Dry Pump
Stoppering (Optional)
Top-Down Pneumatic
Defrost Type
Hot Gas
Refrigerant Type
CFC Free
Condenser Type
Internal

APPLICATION EXAMPLES

  • Laboratory research and development and/or small production freeze drying
  • Diagnostic kits
  • 96 well plates
  • Serum bottles and vials
  • Bulk products for analysis – plant material, organic tissue, waste products

OPTIONAL COMPONENTS

Advantage-Plus.JPG

ACCESSORIES

Shellbath - Brochure (pdf)

Software & Printers
357376 Wizard Automated Control System Software Only : Requires customer to supply a PC (Pentium 120 MHz, 1 gig H.D., 16 meg. RAM, VGA monitor, color printer and proper printer driver, Windows Interface).
358085 Wizard Computer Workstation - Recipe Management, synoptic data screen, data logging and graphing. Includes computer, monitor, color printer and software for running one Wizard. (Requires Wizard Control System).
INS Installation of software on computer provided by customer and shipped to VirTis. (computer must meet VirTis specifications and be shipped to VirTis for complete Q.C. testing). RECOMMENDED FOR ALL SOFTWARE ONLY PURCHASES
LP Line Printer package - for Wizard 1.0 includes interface, printer, and cable (Panasonic Printer). Data printout includes run time, shelf temperature, condenser temperature, two product probe temperatures and vacuum in millitorr.
445681 Line Printer package - Includes Latest Epson LX300+ line printer, 25 pin DBM to 25 pin DBF RS232 cable. Printer is configured and tested prior to shipment for plug and play connection to Freeze Dryer w/ Wizard 2.0. Data includes Shelf, Condenser, Probe Avg, Probes (up to 8 as purchased), Vac1, Vac2 (optional as purchased).
RV Remote View Option. Allows for monitoring and controlling the Workstation from any remote PC through an internal modem. PC Anywhere is installed and configured on purchased Workstation. Modem for remote computer is not supplied.
Stoppering & Clean Room
SC Stoppering Configuration - Unit will use pneumatic top down stoppering platen that compresses the shelves from the top down, for stoppering vials under vacuum. 60psi air or gas required for operation.
CL-A Clean Room Flanging Narrow Configuration *Includes only partial panel enclosure.
100005407 Latching Kit for AdVantage Plus - 3 Shelf to 2 Shelf. Shelf clearance with latch kit installed is 2.56" (65mm) - 2 shelves.  Kit includes 8 spacers. Requires stoppering configuration.  For units manufactured after June, 2011.
100005408 Latching Kit for AdVantage Plus - 2 Shelf to 1 Shelf.   Shelf clearance with latch kit installed is 5.56" (141mm) - 1 shelf.  Kit includes 4 spacers.  Requires stoppering configuration.  For units manufactured after June, 2011.
Vacuum Pump
2005SD 107 LPM Vacuum Pump
448303  Oil Mist Eliminator
100002891 Filter Trap Assembly, includes trap and stand. For AdVantage and Benchtop freeze dryers and freestanding application.
378451 Soda Sorb Filter Cartridge - for VISITRAP filter housing, p/n 100002890 and filter traps p/n 100002891 & 100004724 purchased after 8-1-09.
378444 Activated Charcoal Filter Cartridge  - for VISITRAP filter housing, p/n 100002890 and filter traps p/n 100002891 & 100004724 purchased after 8-1-09.
430272 Molecular Sieve Cartridge for Water Vapor (Filter Cartridge)  for VISITRAP filter housing, p/n 100002890 and filter traps p/n 100002891 & 100004724 purchased after 8-1-09.
Additional Accessories
MVP MVP Product Probes - for placing probes into small sample vials for product temperature analysis while providing virtually no thermal path to the product.Customer to supply: stopper size; length of Guide tube; length of thermocouple wire; type of plug. Additional cost for steam.
WM Manual drying rate windmill - Allows the end user to determine the end of the drying cycle by viewing the windmill through the acrylic door. NOT available on AdVantage Plus.
352005 Flask Safety Shroud ASM for use with AdVantage freeze dryer.
352013 Flask Shelf Assembly for use with AdVantage freeze dryer.
352070 Air Compressor for AdVantage Stoppering Configuration.
375481 Lab Cart/Galvanized Steel w/o Power Strip
448082 Replacement Gasket - AdVantage Plus and AdVantage door gasket
Trays and Rack
351973 Replacement PETG Plastic Product Tray - 10" x 14"
351981 Stainless Steel Tray 10" x 14" for AdVantage 2.0
100002089 Stainless Steel Tray 10" x 14" for AdVantage Plus
351999 Removable bottom stainless steel tray (10" X 14") for use with AdVantage Freeze Dryer. Allows vials to sit directly on the shelf for better heat transfer.
401357 1" Low profile removable bottom stainless steel tray for use with AdVantage Freeze Dryer. Allows vials to sit directly on the shelf for better heat transfer.
363002 3/4" inch removable bottom tray
434416 Stainless Steel Filter Seal Tray with locking rails
400664 Thermaguard Rack, 1"
400671 Thermaguard Rack, 11/2"
400688 Thermaguard Rack, 2"
400695 Thermaguard Removable Bottom Stainless Steel Tray, 1", 10" x 14". Triple rings help dispel edge effects during drying by reflecting energy from the chamber walls and the plastic resin door away from the vials.
400701 Thermaguard Removable Bottom Stainless Steel Tray, 1½", 10" x 14". Triple rings help dispel edge effects during drying by reflecting energy from the chamber walls and the plastic resin door away from the vials.
400718 Thermaguard Removable Bottom Stainless Steel Tray, 2", 10" x 14". Triple rings help dispel edge effects during drying by reflecting energy from the chamber walls and the plastic resin door away from the vials.
Validation/Qualification
VALWKBK-A
Validation Guide and Workbook for AdVantage/AdVantage Plus. Qualification (IQ/OQ) protocols are designed to provide an acceptable degree of confidence that the purchased equipment meets the functional and design specifications as expressed by the manufacturer. All activities are developed to follow a sequential progression as items are reviewed and/or tested. Package includes life cycle documentation and calibration certificates.
 

LITERATURE & ADDITIONAL SPECIFICATIONS

 

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Presenter: Mark Shon

Importance of Controlling Nucleation Temperature During the Freeze Step


23 Feb 2012
9 AM & 2 PM ET

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Instructor: Dr. Jeff Schwegman

Lyophilization Cycle Development & Optimization:
A Hands On Laboratory Course


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Sessions Added!

June 5-8, 2012
Oct 23-26, 2012


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